DNA origami: A precise measuring tool for optimal antibody effectiveness

(Karolinska Institutet) Using DNA origami — DNA-based design of precise nanostructures — scientists at Karolinska Institutet, Sweden, in collaboration with researchers at University of Oslo, Norway, have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system. The study, which is published in the journal Nature Nanotechnology, may be of significance to the development of vaccines and immunotherapy used in cancer.