Powerful microscope captures first image of nanoscaffold that promotes cell movement

(Sanford Burnham Prebys Medical Discovery Institute) Using one of the most powerful microscopes in the world, scientists from SBP and UNC-Chapel Hill have identified a dense, dynamic and disorganized actin filament nanoscaffold — resembling a haystack — that is induced in response to a molecular signal. This is the first time researchers have directly visualized, at the molecular level, a structure that is triggered in response to a cellular signal — a key finding that expands our understanding of how cells move. The study was published in the PNAS.